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A 20-year-old woman presents with a painful lower lip lesion. Examination reveals grouped vesicles on an erythematous base,

A 20-year-old woman presents with a painful lower lip lesion. Examination reveals grouped vesicles on an erythematous base, and you make the diagnosis of herpes labialis. Patient reports recurrent episodes several times per year since she was a child. She has no history of immunosuppression. She desires episodic treatment for recurrent lesions. Which of the following is the most appropriate therapy? Acyclovir 400 mg five times per day, to start one week after onset Famciclovir 750 mg twice daily for seven days Imiquimod 5% cream applied three times per week at bedtime Valacyclovir 2 g twice daily for one day, to start at first sign of symptoms

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