What is the first-line therapy for osteoarthritis and the mechanism of action?
Order Instructions
Sally is a 50-year-old female who has been a jogger for
several years. She has recently been diagnosed with
osteoarthritis. She has been taking ibuprofen for 3 months
but states that “it does not help” and hurts her stomach.
The health care provider prescribes celecoxib (Celebrex) 100
mg orally twice a day.
a. What is the first-line therapy for osteoarthritis and the
mechanism of action?
b. Sally expresses concern about all the recent news about
heart problems and celecoxib (Celebrex). What information
should be included in a teaching plan to help her
understand about taking celecoxib and the benefits and
risks?
c. Ibuprofen and celecoxib are both nonsteroidal anti-
inflammatory drugs. Explain how they are similar and
different
Submission Instructions:
Your initial post should be at least 500 words, formatted and cited in current APA style with support from at least 2 academic sources. Your initial post is worth 8 points.
You should respond to at least two of your peers by extending, refuting/correcting, or adding additional nuance to their posts. Your reply posts are worth 2 points (1 point per response.)
All replies must be constructive and use literature where possible.
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