Ovarian Cancer (OC) is the deadliest form of Gynecological cancers
Each student must turn-in a one page report through SafeAssign (4 pts) by October 30, 2022 at 11:59pm. Cancer is a leading cause of death worldwide, accounting for nearly one in six deaths. Ovarian Cancer (OC) is the deadliest form of Gynecological cancers. Recent discoveries have increased our understanding of the molecular, cellular and the clinical biology of OC, ultimately leading to new therapeutic opportunities. Through the PBLQs stated below, discuss the key molecular players that have been discovered and targeted, and provide the best targeted therapy against OC Reference: "Molecular-targeted therapies for ovarian cancer: prospects for the future". The pdf of the manuscript can be downloaded at this web link: https://link.springer.com/article/10.1007/$10147-012- 0461-1 B. Key points to remember during online team discussions: a. Discuss the major molecular signaling pathways associated with development and progression of ovarian cancer. b. Discuss how targeting key factors in these pathways offers a window of opportunity to inhibit growth of ovarian cancer cells. C. Provide your own explanation and conclusion about the most promising therapeutic approach against OC. C. Format of the report should be verified with SLSC staff (0.5 pts): Introduction (1/4 page): Describe briefly OC and its incidence. (1 pt) Discussion (1/2 page): Discuss the major molecular signaling pathways involved in the onset and progression of DC. (2 pts) Conclusion (1/4 page): Which therapy do you favor and why? (1 pt) References: Include at least THREE PEER-REVIEWED REFERENCES (the source of the information you used to write your report) in the following Format: Stanchev 5, Stamenov N, Kirkov V, Dzhambazova E, Nikolov D, Paloff A. 2020. Differential collagen expression in kidney and heart during hypertension. Nature 121(1):73-78.
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