solve genetic problems with explanation
#1. Sex-linked Inheritance! Problems EX 1: “Bent” is a dominant X-linked gene in mice. tI results in a short, crooked tail. It’s a recessive allele that produces normal tails. If a normal-tailed female is mated to a bent-tailed male, what are the phenotypic and genotypic ratios for the next generation of baby mice? EX2: In humans, the gene for normal blood clotting is dominant to the gene for hemophilia. This gene is on the X chromosome. A woman heterozygous for the trait (a carrier) marries a man with hemophilia. What is the probability of the couple having: 1. a normal (non-carrier) daughter? 2. a normal son? 3. a hemophilic son? 2. Suppose that a normal woman marries a man with hemophilia. What is the probability of the couple having a hemophilic son, and a hemophilic daughter? EX3: A certain form of muscular dystrophy is inherited as a sex-linked, recessive gene. Jack has muscular dystrophy. (Neither of his parents has this disease.) Jane, Jack’s wife, does not have muscular dystrophy, but her father does. What fraction of their daughters would you expect to have muscular dystrophy? What fraction of their sons would you expect to have muscular dystrophy? EX4: In humans, the gene for normal blood clotting is dominant to the gene for hemophilia. Persons with hemophilia do not have the correct blood proteins for normal blood clotting. This gene is on the X chromosome. Suppose that a woman heterozygous for the trait (but with normal blood clotting) marries a man with normal blood clotting. Determine the following probabilities: a The probability of getting a hemophilic child is _________________ b) The probability of getting a “carrier” (heterozygous) child _______________ c) The probability of getting a normal (neither hemophilic nor carrier) child __________ d) The probability of having a normal son ______________ e) The probability of having a hemophilic son _______________ ) The probability of having a son that is a carrier ____________________
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