If your drug is not part of the ICER report, use one of the new therapies as a substitute for your drug. To accomplish this, you must:

If your drug is not part of the ICER report, use one of the new therapies as a substitute for your drug. To accomplish this, you must:

a. Review the basic model description and methodology used by ICER

i. Key Comparative Clinical Effectiveness Parameters

ii. Methodology for Estimating QALYs, Costs, and other key outcomes of the review

b. Evaluate the findings ICER reported (both CUA and BIM)

i. Consider the WTP thresholds provided by ICER and the drugs ability to achieve these thresholds.

ii. What does the results of the BIM tell us that is useful? How should the manufacturer and payer interpret the BIM provided in ICER?

iii. Should the manufacturer think positively or negatively about the findings of the ICER report? Provide rationale and direct examples of concerns that exist in the ICER report.

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