Genetics Question
Biology 420 – Genomics Journal Club paper summary Name:____________________________________ Date:_____________________ Paper:____________________________________ JC#:______________________ You can find the paper here: Read the 2 papers below: DNA Confirms Oral History of Swahili People – The New York Times (nytimes.com) Entwined African and Asian genetic roots of medieval peoples of the Swahili coast | Nature Why are we doing this? Professional scientists are part of an on-going conversation that stretches back for several centuries. The medium for that conversation is scientific articles, where new data is presented, put into historical context, and used to generate new models. The process of peer review serves as a check on the validity of the data and logic of the conclusions. Peer review happens both before and after a paper is published, in order to keep the conversation going. As developing scientists, critical evaluation of the literature is an important skill. Here, you will serve as post-publication reviewers, evaluating papers for validity and put the conclusions into context. This will give you new models of virology, a better understanding of the methods of this field, and opportunities to develop the skills needed for professional scientists. This can be incredibly challenging in genomics. Focus on what you can understand easily and what you can learn with a little bit of effort. Do NOT attempt to understand all the pieces in one sitting. Reading papers easily requires training and practice. Treat it like preparing for an athletic event or a concert. Start slow and be persistent. ————————————————————————–What should I do? Answer all of the following questions (2 points each). Please type your answers in the space below each question. Your answers are due BEFORE the class discussion. The remaining 5 points will come from your engaged participation in the class conversation. Q1: Understanding human ancestry and identity relies on many “ways of knowing”. This is partly why college students are required to take General Education classes. Using the NYTimes article and your own experience, how do “we” know who “we” are? How do “you” know who “you” are? Q2: Considering your answer in Q1, which types of information or data do you value most highly? How does that compare to the ways that the authors of these paper value different types of information? Q3: The study of non-White and non-Western communities often recapitulates and reinforces colonialism. Reflect on the author composition and methods of this paper. How do they approach community-embedded vs. colonialist science? Q4: The authors use both ancient and modern genomes in this study. What information is provided by each and how might that affect their conclusions about the composition of the genomes studied here? Q5: The study concludes that the genomic analysis provides support for mixing between Persian males and African females over 1000 years ago. What evidence supports this claim? Grad Students: How can genomic data from modern people be used to understand individual family history or more recent migrations?
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