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May 1, 2024

A 62-year-old male patient was seen by his family GP, presenting with low-grade fevers, night sweats, and fatigue for 3 weeks

A 62-year-old male patient was seen by his family GP, presenting with low-grade fevers, night sweats, and fatigue for 3 weeks. The patient had a history of a heart murmur but had never undergone extensive evaluation. He had been in generally excellent health with normal exercise tolerance. Approximately 6 weeks ago, he underwent an uncomplicated extraction of an impacted wisdom tooth but received no antibiotics prior to the procedure. The patient was admitted to the hospital, and blood samples were drawn. An echocardiogram revealed a bicuspid aortic valve with an 8-mm mobile vegetation on the anterior cusp.Modern identification techniques, such as MALDI-TOF have revolutionised microbiology in diagnostic laboratories. Discuss how MALDI-TOF can be used to aid the identification of the pathogen responsible for this patient’s infection and the advantages this has over traditional methods. (approx. 600 words essay)

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