What type of readings on a PFT indicate asthma?

Peer Responses:

• Asthma is a chronic respiratory disorder which is mainly characterized by inflammation and narrowing of the airways, which lead to “wheezing, breathlessness, chest tightness, and coughing attacks” in recurrent episodes (Reddel et al., 2021).The underlying etiology of the disease is multifactorial, which is based on the interactions of genetic predisposition and environmental factors. The contribution of specific genes to the disease susceptibility is well known; however, allergens, air pollution, respiratory infections, and tobacco smoke are among the most important environmental triggers of the development of asthma (Reddel et al., 2021). Regarding the epidemiology of asthma, it is among the most widespread chronic conditions that affect children on a global scale, and its prevalence differs among diverse populations and regions. It is usually a process that starts in childhood, but it can happen at any point in one’s life. Boys exhibit a greater prevalence of asthma in their childhood years, but adulthood may change this condition.
• Asthma pathophysiology, as a result of airway inflammation, is characterized by bronchial hyperresponsiveness and airflow limitation. The production of inflammatory mediators, such as histamine, leukotrienes, and cytokines, by the immune system is the cause of airway inflammation and smooth muscle contraction, leading to bronchoconstriction and airway narrowing (Sinyor & Perez, 2023). Clinical manifestation of asthma in children could be different from others in terms of intensity and duration. For instance, airflow obstruction leads to recurrent coughing, wheezing, shortness of breath, and chest tightness, which might be aggravated by physical exercise, allergens, cold air, or respiratory infections.

The diagnosis of asthma in children involves taking a detailed medical history, carrying out a physical examination, and performing pulmonary function tests like spirometry and peak flow measurement. Besides, there could be some tests, like allergy testing or imaging studies, that could be required in specific cases to find out the particular triggers or complications (Akar-Ghibril et al., 2020). The nonpharmacological treatment of asthma in children covers the avoidance of triggers and the improvement of environmental management methods such as allergen avoidance, smoking cessation, and maintaining good indoor air quality. Education could be oriented towards the child and caretaker, and it should be about empowering them to recognize and manage the symptoms of asthma, identify the early signs of exacerbation and have an asthma action plan.

The pharmacological management of asthma in children includes the use of long-term medications that are aimed at controlling airway inflammation and preventing the symptoms (Reddel et al., 2021). Fast-relief medications, such as “short-acting beta-agonists” and “oral corticosteroids” are prescribed to address acute symptoms and to control the occurrence of exacerbations. The follow-up care of children with asthma is of utmost importance to ensure that the disease is controlled, medication regimens are adjusted accordingly, and that children and their caregivers receive the education and support they need to have the best possible outcomes and quality of life. Regular follow-up visits with healthcare providers can be used for control checking, treatment evaluation, and adjustment of management plans when necessary.

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