A 57 year old patient was recently started on Methotrexate for Rheumatoid Arthritis. She is feeling less pain, but verbalizes

A 57 year old patient was recently started on Methotrexate for Rheumatoid Arthritis. She is feeling less pain, but verbalizes concern about the side effects and wants to understand how the medication works. As a nurse practitioner, you discuss the mechanism of action. Which of the following statements is best. Question 2 options: The pain relief is due to inhibiting an intracellular enzyme inside cells that line the joint cavity which decreases inflammation The pain relief is due to blocking interleukin-1 receptors which cause inflammation. All of the responses are correct. The pain relief is the result of immunosuppression secondary to reducing the activity of the B & T lymphocytes.