Abrienda Perez, a 55-year-old teacher, comes to the office complaining of trembling of her hands, a shuffling gait, and occasional drooling.

Abrienda Perez, a 55-year-old teacher, comes to the office complaining of trembling of her hands, a shuffling gait, and occasional drooling. After many tests, she is diagnosed with Parkinson’s disease. She has some concerns and questions about her medication regime. The health care professional explains to Abrienda that catechol-O-methyltransferase (COMT) inhibitors allow the patient’s dose of levodopa to be lowered and decrease the incidence and/or severity of dose-related side effects of levodopa. Which medication is a COMT inhibitor? a. Entacapone (Comtan). b. Trihexyphenidyl (Artane). c. Ropinirole (Requip). d. Benztropine (Cogentin).