Patient 1234 (weight 70 Kg) is to receive a drug by multiple IV bolus doses. For optimal treatment drug concentration

Patient 1234 (weight 70 Kg) is to receive a drug by multiple IV bolus doses. For optimal treatment drug concentration should be kept between Cpmax 10 mg/L and Cpmin 1 mg/L. This drug has an apparent volume of distribution of 1 L/Kg and an elimination rate constant of 0.1 hr-1 (Clearance = 0.1 L/kg.hr). First calculate the dosing interval, tau. Start with a loading dose of mg as an IV Bolus and a maintenance dose of mg as an IV Bolus every hour.

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