Pharmacokinetic actions are mediated through the hepatic and gut drug-metabolizing system known as the cytochrome P540 (CYP) enzyme system.

Pharmacokinetic actions are mediated through the hepatic and gut drug-metabolizing system known as the cytochrome P540 (CYP) enzyme system.

Please answer the following questions, assigned by the first letter of your last name. Select psychiatric medications that you would likely prescribe or encounter frequently in your practice. Include at least two references other than Stahl in your answers. Also, please write two test questions covering the information in your initial post.

Last Name H–O: State what the CYP 3A4 enzyme is, why it is important, and what it does in the body. List common medications, foods, herbs, and/or substances that inhibit and induce this enzyme; include any major substrates (specifically psychiatric drugs you would encounter) and any important medication restrictions regarding this enzyme.