Altered Immune System and Altered Inflammatory Response

Altered Immune System and Altered Inflammatory Response

NR507

NR 507 DeVry Week 1 Discussions Latest

Week 1: Altered Immune System and Altered Inflammatory Response

Part One

This week’s graded topics relate to the following Course Outcomes (COs).

1 Analyze pathophysiologic mechanisms associated with selected disease states. (PO 1)

2 Differentiate the epidemiology, etiology, developmental considerations, pathogenesis, and clinical and laboratory manifestations of specific disease processes. (PO 1)

3 Examine the way in which homeostatic, adaptive, and compensatory physiological mechanisms can be supported and/or altered through specific therapeutic interventions. (PO 1, 7)

4 Distinguish risk factors associated with selected disease states. (PO 1)

5 Describe outcomes of disruptive or alterations in specific physiologic processes. (PO 1)

6 Distinguish risk factors associated with selected disease states. (PO 1)

7 Explore age-specific and developmental alterations in physiologic and disease states. (PO 1, 4)

Discussion Part One (graded)

John is a 19-year-old college football player who presents with sneezing, itchy eyes, and nasal congestion that worsens at night. He states that he has a history of asthma, eczema and allergies to pollen. There is also one other person on the football team that has similar symptoms. His vitals are BP 110/70, P 84, R 18, T 100 F. Write a differential of at least five (5) possible items from the most likely to less likely. For each disease include information about the epidemiology, pathophysiology and briefly argue why this disease fits the presentation and why it might not fit the presentation Week 1: Altered Immune System and Altered Inflammatory Response

Discussion Part Two

A patient has been admitted into the emergency room that was in the passenger side of a car that collided with another car head on. The patient is pale, barely conscious and has a weak and thread pulse. An IV is started. The vitals are BP 80/50, P 140, T 96.0 and R 26. As the team fights to keep the patient alive they have to remove the spleen. Blood is given but it has been mistyped. A transfusion reaction occurs. Describe the type of hypersensitivity reaction that has occurred and discuss the molecular pathophysiology of the specific type of hypersensitive reaction you have chosen.

In the event that this patient survived the car accident and the transfusion reaction which organs are most likely to be damaged and why?

Discussion Part Three

This week’s graded topics relate to the following Course Outcomes (COs).

1 Analyze pathophysiologic mechanisms associated with selected disease states. (PO 1)

2 Differentiate the epidemiology, etiology, developmental considerations, pathogenesis, and clinical and laboratory manifestations of specific disease processes. (PO 1)

3 Examine the way in which homeostatic, adaptive, and compensatory physiological mechanisms can be supported and/or altered through specific therapeutic interventions. (PO 1,

4 Distinguish risk factors associated with selected disease states.(PO 1)

5 Describe outcomes of disruptive or alterations in specific physiologic processes. (PO 1)

6 Distinguish risk factors associated with selected disease states. (PO 1)

7 Explore age-specific and developmental alterations in physiologic and disease states. (PO 1, 4)

Discussion

A 44-year-old patient presents with lump in the chest of approximately 2 cm in diameter. There is a slight dimple over the location of the lump and when the lump is manipulated it seems to be attached to the surrounding tissue. A lumpectomy is performed and the mass is sent to pathology. The pathology report comes back and the mass is confirmed to be an estrogen receptor negative, a progesterone receptor negative and a her2/neu receptor positive breast cancer.

What are some of the risk factors for breast cancer? What tumor suppressor genes are associated with breast cancer?

What tumor oncogenes are associated with breast cancer?

Compare and contrast tumor suppressor genes from oncogenes?

ADDITIONAL INFORMATION;

Altered Immune System and Altered Inflammatory Response

Introduction

Arthritis is a common and debilitating disease that can affect any joint in your body. Arthritis is a general term for inflammation of the joints, but it can also refer to other conditions such as osteoarthritis and rheumatoid arthritis. While there are many different types of arthritis, they all affect the same parts of your body at the same time: bones, cartilage and ligaments. That’s why it’s so important to find out what makes your condition worse or better so you can treat it properly.

Overview

• Arthritis is a common condition that affects more than 100 million people in the United States.

• There are many conditions that cause arthritis, including rheumatoid arthritis and psoriatic arthritis.

• The immune system plays an important role in the development of these diseases.

• The inflammatory response is part of your body’s immune response; it allows you to fight off infections and other harmful substances (such as viruses).

Symptoms

The most common symptoms of an altered immune system and inflammatory response are:

• Pain, swelling, and stiffness in the joints

• Redness and warmth of the skin

• Swelling in the lymph nodes (lymph nodes are small glands that help filter out foreign substances)

If you have these symptoms, it’s important to see a doctor. They can help determine if you have an infection or another health issue.

Causes

• Genetic predisposition – Some people are born with a genetic predisposition to certain diseases. They may have a gene called HLA-B27 that makes them more likely to get ankylosing spondylitis (AS), for example.

• Dietary factors – Some foods can affect the immune system and lead to inflammatory diseases like rheumatoid arthritis, lupus and psoriasis. These include:

• Sugar, including fructose, glucose and sucrose; added sugars in drinks such as soft drinks or fruit juice; refined carbohydrates such as white flour products

Diagnosis

The diagnosis of IBD is based on the symptoms and patient’s history, physical examination, blood tests and other diagnostic procedures.

• A thorough history includes questions about your diet (including if you have a family history of IBD), lifestyle factors such as stress level or smoking status; travel plans; medications taken during treatment; whether you have been exposed to a person with an infectious disease such as tuberculosis; any recent changes in diet or exercise habits; symptoms (such as diarrhea) that occur before an injury/injury-related stressor occurs [1].

• When evaluating for IBD, it’s important to look at several different aspects of the patient’s health such as weight loss due to fluid loss from diarrhea or constipation [1]..

Treatment

You may be wondering what treatment options are available for an altered immune system. While there are many different treatments, they all have their pros and cons. Some treatments are more effective than others, some are more expensive than others, and it is important to find the right treatment for you.

The most common treatment for an altered immune system is antibiotics. These medications are designed to target any bacteria that may be causing the infection. They are usually taken orally, but some may also be administered intravenously. It is important that you take all of your antibiotics as prescribed by your doctor in order to prevent resistance from developing.

There is a large variety of conditions that cause arthritis and affect the immune system.

The immune system is a complex system made up of many different cells, which are responsible for protecting the body from disease. The immune system protects against infections by attacking bacteria and other microbes that may cause illness. It also fights cancerous tumors and viruses that infect your body.

The human body has several types of cells in its immune system: white blood cells (leukocytes), red blood cells (erythrocytes), platelets, mast cells and lymphocytes. Each type plays an important role in defending against foreign invaders–in particular, leukocytes kill germs while mast cells release chemicals called histamine when they sense an allergen or irritant; platelets form clots to stop bleeding; erythrocytes carry oxygen throughout your bloodstream; lymphocytes fight infection by engulfing bacteria or viruses- and even help repair damaged tissue after injury!

Conclusion

The treatment of arthritis can be complex, and it is important to get a diagnosis as soon as possible in order to start the best treatment plan. There are many different types of arthritis that can affect your joints, including osteoarthritis and rheumatoid arthritis. The sooner you are diagnosed with one of these conditions, the sooner you can start taking steps towards improving your health and treating symptoms with medication or physical therapy.