Describe the plasma membrane structure using the fluid mosaic model

OL Lab 3: Cell Membrane and Transport: Learn how transporters keep cells healthy

Learning Objectives:

• Describe the plasma membrane structure using the fluid mosaic model

• Recognize the relative permeability of lipid bilayers to different classes of molecule

• Compare active and passive transport of molecules

• Identify the 3 modes of active transport and the different classes of ion channel and carrier molecules

• Relate the expression of specific transport proteins to the cell’s role

Introduction:

A variety of substances move in and out of the cells through the plasma membrane. Membrane transport is vital for cellular activities. The cells need to be healthy for the body to work efficiently. From filtration in the kidneys to the contraction of muscles during exercise, membrane transport contributes to many processes. In this simulation, you will learn about the structure and function of the cell membrane, and discover why membrane transporters are vital for healthy cells and the function of organ systems.

In the first part of your mission, you will be introduced to the concepts of selective permeability and the fluid mosaic models of the plasma membrane. You will explore why cells need specialized transporter proteins to transport cargo molecules across their membranes. While some molecules can diffuse across the cell membrane, most molecules require a transporter protein to enter or leave the cell.

In the later part of the simulation, you will set up a fluorescence microscopy experiment to learn how the channels, carriers, and pumps that exist in the membrane ensures that only the right molecules enter under the right conditions and help not only to keep the cell healthy but also help organ systems to function.

Part 1: Complete Labster Cell Membrane and Transport

BIOS251 OL, Week 3 Lab

Name:

Part 2: Report and Reflection

Purpose: Describe in your own words and in complete sentences, the purpose of this experiment.

Observations: List 2 observations you have made in this simulation.

Answer all the questions below:

1. In complete sentences and in your own words define the following cellular transport: (2 points)

a. Diffusion:

b. Osmosis:

c. Facilitated diffusion:

d. Active transport:

BIOS251 OL, Week 3 Lab

Name:

2. Using the figure below, identify the cellular structures and its function.(6 points)

Cell Structure Functions

A

B

C

D

E

BIOS251 OL, Week 3 Lab

Name:

F

G

H

I

BIOS251 OL, Week 3 Lab

Name:

3. What is tonicity and how does it affect the condition of the cell? (1 point)

4. When is a hypotonic IV solution administered to patients? Why? (1 point)

5. Reflection: Reflect on at least 2 key concepts you have learned from this simulation. How would you relate it to the physiological functions of the body?

Grading Rubric:

Activity Deliverable Points

Part 1 Complete simulation 15

Part 2 Complete lab report and answer questions • Purpose (1 point) • Observation (2 points) • Questions (10 points) • Reflection (2 points)

15

Total Complete all lab activities 30

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