UTI who presented in emergency room will chief complaint of not feeling well, not moving her upper extremity, weakness and slurred speech. She is disoriented and cannot provide history. CT

84-year-old women with a past medical history of memory issues, emphysema, HTN, hyperlipidemia, UTI who presented in emergency room will chief complaint of not feeling well, not moving her upper extremity, weakness and slurred speech. She is disoriented and cannot provide history. CT was negative. However, MRI brain demonstrated small acute infarct within the right posterior caudate.
Question: Describe the relationship between any disease or risk factors in PMH that may have contributed to the development of the problem (which disease likely developed FIRST that began the “domino effect?).