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February 6, 2023

A 50-year-old woman with schizophrenia is admitted with mutism. Interview attempts remain unsuccessful, as she does not verbally respond to questions. She is observed sitting still in one

A 50-year-old woman with schizophrenia is admitted with mutism. Interview attempts remain unsuccessful, as she does not verbally respond to questions. She is observed sitting still in one place for several hours, and when her posture is changed by nursing, it remains in the same position until she is moved again. Her vitals show a blood pressure of 112/62 mmHg, a heart rate of 66 beats per minute, a respiratory rate of 14 breaths per minute, and a temperature of 98°F (36.7°C). The physical exam is notable for mild rigidity in the upper extremities. Lab investigations show normal ammonia, TSH, creatine kinase, and basic metabolic panel. Medication treatment is initiated. What is the mechanism of action for the most likely medication administered?
A. Potentiate GABA receptor function by increasing chloride channel opening frequencyB. Blockade of postsynaptic dopaminergic D2 receptorsC. Blockade of voltage-dependant sodium channelsD. Noncompetitive NMDA receptor antagonist

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