What does it mean? What does it suggest about the impact of synthetic opioids on opioids that are prescribed and heroin drug overdose deaths

All these questions are about figure 2:

What does it mean? What does it suggest about the impact of synthetic opioids on opioids that are prescribed and heroin drug overdose deaths? Why?

FIGURE 2. Age-adjusted rates* of drug overdose deaths involving prescription opioids,$ heroin," cocaine,** and psychostimulants with abuse potential, with (A) and without (B) synthetic opioids other than methadone$s,11 – United States, 2013-2019 A B 4.5 4.5- 4.0- 4.0- 3.5- 3.5- 3.0- 3.0- 2.5- 2.5- Deaths per 100,000 population Deaths per 100,000 population 2.0- 2.0- 1.5- 1.5- MININIE 1.0- 1.0- 0.5- 0.5- 0.0 0.0- 2013 2014 2015 2016 2017 2018 2019 2013 2014 2015 2016 2017 2018 2019 With coinvolvement of synthetic opioids Without coinvolvement of synthetic opioids Prescription opioids – Heroin . Cocaine – Psychostimulants with abuse potential

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