You see a patient with complaints of midline axial neck pain and headaches for 3 months. The pain does not travel into the upper extremities and there are no signs of sensory/motor dysfunction. Which of the following is the most likely core defect?

Question 1You see a patient with complaints of midline axial neck pain and headaches for 3 months. The pain does not travel into the upper extremities and there are no signs of sensory/motor dysfunction. Which of the following is the most likely core defect?

Fibromyalgia

Cervical spondylosis

Muscle spasm

Neuroforaminal stenosis with impingement of exiting cervical nerve roots

Question 2A patient in the clinic is worried about having fibromyalgia. You would begin your diagnosis by exclusion by assessing for all of the following EXCEPT:

Rheumatism

low-grade systemic inflammation

Thyroid disease

Osteoarthritis

That’s not correct

Question 3Which protein, absent in muscle cells of Duchenne muscular dystrophy, mediates the anchoring of skeletal muscle fibers to the basement membrane?

Syntrophin

Laminin

Dystrophin

Troponin

Question 4What is the most common malignant bone tumor diagnosed during childhood?

Chondrosarcoma

Fibrosarcoma

Ewing Sarcoma

Osteosarcoma

Question 5What is a primary defect in osteoarthritis?

Stromelysin and acid metalloproteinase breakdown articular cartilage.

Immunoglobulin G (IgG) destroys the synovial membrane.

Synovial membranes become inflamed.

Cartilage-coated osteophytes create bone spurs.

Question 6Which of the following is most consistent with suspicion for rheumatoid arthritis (RA)?

Bilateral large and small joint involvement, pain worse upon wake and with activity

Unilateral or Bilateral large joint involvement, pain worse upon wake and at bedtime

Unilateral or Bilateral small joint involvement, pain worse at bedtime and with activity

Diffuse body wide pain in multiple joints, worse with physical activity

Question 7What does a Ewing sarcoma arise from?

Bone marrow

Bone-producing mesenchymal cells

Metadiaphysis of long bones

Embryonal osteocytes

Question 8Which bone cells are large and multinucleated and contain lysosomes filled with hydrolytic enzymes?

Osteoblasts

Osteoclasts

Osteocytes

Fibrocytes

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