A case-control study investigated the association between illicit drug use during pregnancy and the development of gastroschisis (a rare birth defect) in newborns from 2011-2014.

A case-control study investigated the association between illicit drug use during pregnancy and the development of gastroschisis (a rare birth defect) in newborns from 2011-2014. Cases were recruited from a specialty clinic that sees patients referred to them from across the region. Controls were sampled from a local obstetrics practice that sees patients from the local neighborhood. Think about the source of controls in this study. Do you think they satisfy the purpose you describe above? Explain. If no, what kind of bias would you expect to see?

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