A study was conducted involving adults in the US who were at high risk for the development of type 2 diabetes.
5. A study was conducted involving adults in the US who were at high risk for the development of type 2 diabetes. The study was designed to answer if a lifestyle intervention (weight loss and exercise) and! or treatment with metformin, a biguanide antihyperglycemic agent, could prevent or delay the onset of diabetes. Volunteers, meeting the protocol eligibility criteria, were randomly assigned to placebo, metformin, or a lifestyle—modification program (with the goals of at least 7% weight loss and at least 150 minutes of physical activity per week). Neither volunteers who were randomly selected for the medication arm (placebo or metformin}, nor study investigators, were aware if the pills the volunteers were assigned to were placebo or metformin. a. What type of study design is this? b. Was this a blinded study? If yes why and which kind? c. What was the exposure(s)? d. What was the outcome measure? e. What was the target population?
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