Someone who has asthma can usually get considerable relief from using their albuterol inhaler, but if they over-use it for several days they can significantly decrease the potency and efficacy of the drug.
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QUESTION: Someone who has asthma can usually get considerable relief from using their albuterol inhaler, but if they over-use it for several days they can significantly decrease the potency and efficacy of the drug.
1. Briefly describe the cellular mechanism(s) that could account for the decrease in potency of albuterol
2. Briefly describe the cellular mechanism(s) that could account for the decrease in efficacy of albuterol
3. You’ve discovered a new drug that inhibits G-protein receptor kinases. How would you determine this inhibitor’s effect on epinephrine’s actions?
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