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November 2, 2022

If you were to test this GHT gene therapy in a clinical trial

If you were to test this GHT gene therapy in a clinical trial, which of the design options below would you choose? Evaluate both options and justify your answer. (5 marks) . Option A: Healthy volunteers assigned randomly into two parallel groups. One group receives placebo, the other receives the GHT gene therapy. Double blind. Trial length is 12 weeks after which participants are no longer monitored. . Option B: Open-label single group, all participants have Parkinson’s disease and receive the GHT gene therapy. Participants are monitored for five years after beginning the trial.

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