Drugs that act by making more acetylcholine (ACh) available at the receptor site, thus allowing ACh to bind and stimulate the receptor

Match each definition with its corresponding term. (Note – not all terms will be used.)

 [ Choose ] Muscarinic receptors Serotonin Dopaminergic drugs Indirect-acting sympathomimetic drugs Direct-acting cholinergic drugs Indirect-acting cholinergic drugs Monoamine oxidase Dopamine Nicotinic receptors Atropine Direct acting sympathomimetic drugs Norepinephrine Alpha and beta receptors Cholinesterase inhibitor Serotonergic receptors Acetylcholinesterase 

Drugs that act by making more acetylcholine (ACh) available at the receptor site, thus allowing ACh to bind and stimulate the receptor

Drugs that bind to the cholinergic receptors and activate them

The enzyme responsible for degrading acetylcholine

 Receptors located post-synaptically in the neuromuscular junction innervated by the parasympathetic nervous system

 

 

 

 

Receptors located post-synaptically in smooth muscle, cardiac muscle and glands innervated by the parasympathetic nervous system the

 

 

 

 

The primary neurotransmitter found in the sympathetic nervous system

 

 

Receptors classified as adrenergic receptors

 

 

Drugs that act by making more norepinephrine available at the receptor site, thus allowing norpeinephrine to bind and stimulate the receptor

 

 

Flag question: Question 2Question 21 pts

 

 

 

What is the most important mechanism responsible for terminating the synaptic effects of norepinephrine?

 

Group of answer choices

 

Reuptake into the presynaptic neuron that released it

 

 

 

Redistribution from the synapse into the interstitial fluid

 

 

 

Uptake by the post-synaptic neuron where the receptors are located

 

 

 

Enzymatic degradation in the synapse and liver

 

 

 

 

 

Flag question: Question 3Question 31 pts

 

 

 

A patient with myasthenia gravis is treated with pyridostigmine. What drug might be used to manage the cholinergic side effects of pyridostigmine in this patient?

 

Group of answer choices

 

atropine

 

 

 

edrophonium

 

 

 

donepezil

 

 

 

bethanechol

 

 

 

 

 

Flag question: Question 4Question 41 pts

 

 

 

Based on each drug’s mechanism of action, which of the following correctly matches a drug with its expected physiological effects (therapeutic and/or adverse effects)?

 

Group of answer choices

 

Pilocarpine can cause constipation, urine retention and bronchial constriction

 

 

 

Neostigmine can cause bradycardia, hypertension and mydriasis (pupil dilation)

 

 

 

Atropine can cause tachycardia, constipation and mydriasis (pupil dilation)

 

 

 

Oxybutynin can cause bradycardia, excessive salivation, and exacerbation of glaucoma

 

 

 

 

 

Flag question: Question 5Question 51 pts

 

 

 

Which of the following pairs correctly matches a drug with its clinical indication?

 

Group of answer choices

 

Varenicline is indicated for management of smoking cessation

 

 

 

Methacholine is indicated for management of myasthenia gravis

 

 

 

Donepezil is indicated for management of overactive bladder

 

 

 

Bethanechol is indicated for management of nausea and vomiting

 

 

 

 

 

Flag question: Question 6Question 61 pts

 

 

 

Which cholinergic receptor is believed to play a significant role in cognition?

 

Group of answer choices

 

M3 receptor

 

 

 

M4 receptor

 

 

 

M2 receptor

 

 

 

M1 receptor

 

 

 

M5 receptor

 

 

 

 

 

Flag question: Question 7Question 71 pts

 

 

 

Which type of cholinergic receptor is believed to be most responsible for normal micturition contraction of the bladder?

 

Group of answer choices

 

M5 receptor

 

 

 

M1 receptor

 

 

 

M2 receptor

 

 

 

M4 receptor

 

 

 

M3 receptor

 

 

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