An individual with testes but female external genitalia present at a fertility clinic.

A man with the genotype 46, XX, SRY-, SOX9+ (i.e., no SRY gene, SOX9 promoter and coding region normal, phenotypic characteristics male) showed up at the fertility clinic. Assume that there is a mutation in the sex determination pathway. Choose whether the mutation is in the male or the female sex determination pathway. In no more than two sentences, suggest a gene where the mutation could be and justify your rationale.

An individual with testes but female external genitalia present at a fertility clinic. What genotype would you predict for this individual (remember that genotype refers to the number of chromosomes and the sex chromosomes, such as 46, XX)? A mutation in what gene could give rise to this phenotype? In one sentence, why does a mutation in this gene give rise to this phenotype?

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