The type of immunity produced by an individual after either natural exposure to the antigen or after immunization against the antigen is:
Question 1 The type of immunity produced by an individual after either natural exposure to the antigen or after immunization against the antigen is:
Answers:
Passive-acquired immunity
Active-acquired immunity
Passive-innate immunity
Active-innate immunity
Question 2Which statement is a description of the characteristics of apoptosis?
Answers:
Programmed cell death of scattered, single cells
Characterized by swelling of the nucleus and cytoplasm
Unpredictable patterns of cell death
Results in benign malignancies
Question 3 The effects of the syndrome of inappropriate antidiuretic hormone (SIADH) secretion include:
Answers:
Solute retention and water retention
Solute retention and water loss
Solute dilution and water retention
Solute dilution and water loss
Question 4 Hypersensitivity is best defined as a(an):
Answers:
Disturbance in the immunologic tolerance of self-antigens
Immunologic reaction of one person to the tissue of another person
Altered immunologic response to an antigen that results in disease
Undetectable immune response in the presence of antigens
Question 5 The most common cause of pulmonary edema is:
Answers:
Right heart failure.
Left heart failure.
Mitral valve prolapse.
Aortic stenosis.
Question 6 A fulminant form of respiratory failure characterized by acute lung inflammation and diffuse alveolocapillary injury is known as:
Answers:
Acute respiratory distress syndrome.
Pneumonia.
Pulmonary emboli.
Acute pulmonary edema.
Question 7 Factors that place patients at HIGH RISK for developing colorectal cancer include:
Answers:
High fiber, low fat diet.
Use of NSAIDS
Postmenopausal estrogen use.
Irritable bowel disease
Question 8 A 40 year old African American woman presents with chest pain and dyspnea. The workup reveals a microcytic anemia and a low reticulocyte count. The most likely diagnosis is:
Answers:
Thalassemia.
Lead toxicity.
Iron deficiency
Vitamin B12 deficiency.
Question 9 Preload is:
Answers:
Resistance to the ejection of blood from the left ventricle.
Wall tension that is related to internal blood vessel radius.
Lower tension curve than normal—a major characteristic.
Pressure generated by the end-diastolic volume.
Question 10 Chemical mediators that induce pain during an inflammatory response include:
Answers:
Tryptase and bradykinin
Leukotrienes and prostaglandins
Prostaglandins and bradykinin
Phospholipase and tryptase.
Question 11 Symptoms of benign prostatic hyperplasia (BPH) are a result of which pathophysiologic condition?
Answers:
Infection of the prostate
Obstruction of the urethra
Compression of the urethra
Ischemia of the urethra
Question 12 The blood cell that carries the carbohydrate antigens for blood type is:
Answers:
Platelets
Neutrophils
Lymphocytes
Erythrocytes
Question 13 The type of antibody involved in Type I hypersensitivity reaction is:
Answers:
IgA
IgE
IgG
IgM
Question 14 An allele with an observable effect is referred to as:
Answers:
Homozygous
Heterozygous
Dominant
Recessive
Question 15 Hepatitis B and Hepatitis C have a common mode of transmission, which is:
Answers:
Fecal
Oral
Parenteral
Fecal-oral and sexual
Question 16 A patient who is diagnosed with a closed head injury has a urine output of 6 to 8 L/day. Electrolytes are within normal limits, but his antidiuretic hormone (ADH) level is low. Although he has had no intake for 4 hours, no change in his polyuria level has occurred. These symptoms support a diagnosis of:
Answers:
Neurogenic diabetes insipidus
Syndrome of inappropriate antidiuretic hormone
Psychogenic polydipsia
Osmotically induced diuresis
Question 17 The echocardiogram you obtained on a 65 year old female revealed characteristics of Hypertrophic Obstructive Cardiomyopathy. The pathophysiology that explains her symptoms of syncope, dyspnea, and worsening fatigue include:
Answers:
Absence of heart murmurs.
Ectatic aorta
Hypertrophied interventricular septum
Large pericardial effusion
Question 18 A patient’s blood gases reveal the following findings: pH, 7.3; bicarbonate (HCO3) 27 mEq/L; carbon dioxide (CO2), 58 mm Hg. This patient has:
Answers:
Respiratory alkalosis
Respiratory acidosis
Metabolic alkalosis
Metabolic acidosis
Question 19 During cell injury caused by hypoxia, an increase in the osmotic pressure occurs within the cell because:
Answers:
Plasma proteins enter the cell.
The adenosine triphosphatase (ATPase)–driven pump is stronger during hypoxia.
Sodium chloride leaves the cell.
Calcium and water enter the cell and disrupt protein synthesis.
Question 20 Which statement is true regarding chromosomes?
Answers:
There are three cell types.
The somatic cell contains 46 chromosomes.
Gametes are diploid cells.
Diploid cells are formed through meiosis.
Question 21 What is usually the first clinical manifestation of breast cancer?
Answers:
Nipple dimpling
Nipple discharge
Enlargement of one breast
Painless lump
Question 22 The clinical manifestations of confusion, convulsions, cerebral hemorrhage, and coma in hypernatremia are due to:
Answers:
High sodium in the blood vessels pulls water out of the brain cells into the blood vessels, causing brain cells to shrink.
High sodium in the brain cells pulls water out of the blood vessels into the brain cells, causing them to swell.
High sodium in the blood vessels pulls potassium out of the brain cells, which slows the synapses in the brain.
High sodium in the blood vessels draws chloride into the brain cells followed by water, causing the brain cells to swell.
Question 23 The most successful treatment for chronic asthma is:
Answers:
Broad-spectrum antibiotics.
Drugs that reduce bronchospasm.
Drugs that decrease airway inflammation.
Avoidance of the causative agent.
Question 24 Which statement is true regarding protein synthesis?
Answers:
Protein synthesis takes place in the cytoplasm.
DNA is replicated in the cytoplasm.
RNA is double-stranded.
RNA contains the same bases as DNA.
Question 25 The mechanism that results in type II hypersensitivity reactions is:
Answers:
Antibodies coat mast cells by binding to receptors that signal its degranulation, followed by a discharge of preformed mediators.
Antibodies bind to soluble antigens that were released into body fluids, and the immune complexes are then deposited in the tissues.
Cytotoxic T lymphocytes or lymphokine-producing helper T 1 cells directly attack and destroy cellular targets.
Antibodies bind to the antigens on the cell surface.
Question 26 When antigens are administered to produce immunity, different routes of administration are considered because:
Answers:
Different routes allow the speed of onset of the antigen to be varied, with the intravenous route being the fastest.
Some individuals appear to be unable to respond to an antigen by a specific route, thus requiring the availability of different routes for the same antigen.
Antigen-presenting cells are highly specialized and thus require stimulation by different routes.
Each route stimulates a different lymphocyte-containing tissue, resulting in different types of cellular and humoral immunity.
Question 27 The Frank-Starling Law is based on the relationship of:
Answers:
Resting sarcomere length to end-diastolic volume.
Tension generation and left ventricular pressure.
Resting sarcomere length to tension generation.
Tension generation and diastolic filling pressure.
Question 28 Factors which create an environment that promotes thrombus formation, known as Virchow’s triad, include:
Answers:
Hypercoagulability, hypervolemia, hypertension.
Hypercoagulability, stasis, endothelial damage.
Hypercoagulability, vasoconstriction, hypotension.
Peripheral edema, pain, fever.
Question 29 Free radicals cause cell damage by:
Stealing the cell’s oxygen to stabilize the electron, thus causing
Stimulating the release of lysosomal enzymes that digest the cell membranes
Transferring one of its charged, stabilized atoms to the cell membrane, which causes lysis
Giving up an electron, which causes injury to the chemical bonds of the cell membrane
Question 30 When examining a new patient, you discover impaired vibratory sense as well as spastic weakness. The patient also reports paresthesia in the fingers and toes. Labs reveal a hemoglobin of 10. You suspect that the diagnosis for this patient is:
Answers:
Vitamin B12 deficiency.
Folate deficiency.
Sickle cell disease.
Aplastic anemia.
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