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October 30, 2022

One of the medications Mrs. G has been prescribed is an acetylcholine esterase inhibitor

I would appreciate an explanation for the three questions below:

1) One of the medications Mrs. G has been prescribed is an acetylcholine esterase inhibitor. In your own words, explain how the pharmacodynamic properties of this medication help manage her condition?

2) It is known that the bioavailability of the drug she has been prescribed with is 36%. She takes a tablet that contains 1.5 mg of the active ingredient twice a day. Determine the daily amount (mg) of active ingredient that reaches her systemic circulation. (Show your calculations.)

3) Considering that 95% of the active ingredient is absorbed from her gastrointestinal system, determine the daily amount (mg) of the drug that undergoes first pass metabolism. (Show your calculations.)

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