RESP 106 Respiratory Pharmacology
Ivy Tech Community College
RESP 106 Respiratory Pharmacology
Homework Number 4
Mucus-controllers, Surfactants, Corticosteroids, & Anti-asthmatic agents
Name: __________________________________ ________ / 22 pts
1. List seven factors that can slow mucociliary transport. 3.5 pts
.
2. What are two indications for the use of N-Acetylcysteine? 2 pts
3. What is the most serious hazard that can occur with the use of N-Acetylcysteine? 2 pts
a. How can the incidence of this hazard occurring be decreased?
4. Pulmozyme is a drug approved for treatment of tenacious sputum in patients with cystic
fibrosis. How does this drug decrease the tenacity of the sputum? 1 pt
5. Why is hypertonic saline thought to improve mucociliary transport? 1pt
6. The force caused by the attraction between like molecules, which occur at the liquid- gas
interface, and that holds the liquid surface intact, is called _________________
__________________. 1 pt
7. What is the primary function of surfactant in the lungs? 1 pt
8. _______________ surfactants are obtained from animals or humans by alveolar wash or
from amniotic fluid. 1 pt
9. Survanta and Infasurf come from ___________ lungs, and Curosurf comes from
_____________ lungs. 1 pt
10. What type of effect do glucocorticoids, also known as steroids, have on the body? 1 pt
11. List six side effects associated with systemic administration of corticosteroids. 3 pts
.
.
12. List three ways to minimize the local side effects of inhaled steroid administration. 1.5
pts
1. .
2. .
3. .
13. Cromolyn sodium is used as a _______________ agent in order to prevent asthma
attacks. 1 pt
14. Explain the benefit of asthmatic patients using a drug such as Cromolyn Sodium to
stabilize the mast cell. 1 pt
15. Name two anti-leukotriene agents that have been approved for use in the United States. 2
pts
1. .
2.
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