Provide a subsequent commentary outlining the key observations, concentrating on the certainty of the individual trial results and the indirect comparison in respect to risk difference.

Provide a subsequent commentary outlining the key observations, concentrating on the certainty of the individual trial results and the indirect comparison in respect to risk difference.

  PEM + LEN (N=352) Pazopanib (N=554) Odds Ratio

(95% CI) Relative Risk 

(95% CI) Risk Difference 

(95% CI)

Any Event 351 (99.7) 538 (97.1) 10.44 (1.38, 79.07) 1.03 (1.01, 1.04) 2.6 (1.1, 4.1)

Diarrhoea 216 (61.4) 321 (57.9) 1.15 (0.88, 1.51) 1.06 (0.95, 1.18) 3.4 (-3.1, 10.0)

Fatigue 141 (40.1) 273 (49.3) 0.69 (0.52, 0.90) 0.81 (0.70, 0.95) -9.2 (-15.8, -2.6)

Hypertension 195 (55.4) 240 (43.3) 1.63 (1.24, 2.13) 1.28 (1.12, 1.46) 12.1 (5.4, 18.7)

Nausea 126 (35.8) 223 (40.3) 0.83 (0.63, 1.09) 0.89 (0.75, 1.06) -4.5 (-10.9, 2.0)

Stomatitis 122 (34.7) 72 (13.0) 3.55 (2.55, 4.94) 2.67 (2.06, 3.45) 21.7 (16.0, 27.4)

Proteinuria 104 (29.5) 89 (16.1) 2.19 (1.59, 3.02) 1.84 (1.43, 2.36) 13.5 (7.8, 19.1)

Vomiting 92 (26.1) 133 (24.0) 1.12 (0.82, 1.52) 1.09 (0.87, 1.37) 2.1 (-3.7, 7.9)

Collepals.com Plagiarism Free Papers

Are you looking for custom essay writing service or even dissertation writing services? Just request for our write my paper service, and we'll match you with the best essay writer in your subject! With an exceptional team of professional academic experts in a wide range of subjects, we can guarantee you an unrivaled quality of custom-written papers.

Get ZERO PLAGIARISM, HUMAN WRITTEN ESSAYS

Why Hire Collepals.com writers to do your paper?

Quality- We are experienced and have access to ample research materials.

We write plagiarism Free Content

Confidential- We never share or sell your personal information to third parties.

Support-Chat with us today! We are always waiting to answer all your questions.