October 13, 2022

Advanced Pharmacology for Care of the Family

I understand the value of doing my own work and learning the skills needed to support my future independent practice as a nurse practitioner. I understand that while there may be opportunities beyond my faculty’s control for me to collaborate or share answers with peers, that it would not benefit my own personal and professional growth to do so. I agree to do my own work and take personal responsibility for my learning.

Group of answer choices

I do

I do not

Flag question: Question 2

Question 24 pts

Using your textbook, match the antibiotic class to the patient care concern for children/adolescents.

Use each option only once by selecting the option that is most true.

Group of answer choices

Commonly used to treat bacterial infections, including otitis media and gonococcal and pneumococcal infections.

[ Choose ] Cephalosporins Tetracyclines Penicillins Aminoglycosides

Common drug used to treat bacterial infections.

[ Choose ] Cephalosporins Tetracyclines Penicillins Aminoglycosides

Should not be used in children younger than 8 years because they may cause permanent discoloration of the teeth.

[ Choose ] Cephalosporins Tetracyclines Penicillins Aminoglycosides

Safe for use against bacterial infections but not commonly used in outpatient settings.

[ Choose ] Cephalosporins Tetracyclines Penicillins Aminoglycosides

Flag question: Question 3

Question 34 pts

Match the drug or drug class that is contraindicated for UTI in the patient population group listed.

Use each option only once by selecting the option that is most true.

Group of answer choices

Trimethoprim/sulfamethoxazole

[ Choose ] Early infancy Throughout pregnancy Third trimester of pregnancy & Older adults with decreased renal function

Nitrofurantoin

[ Choose ] Early infancy Throughout pregnancy Third trimester of pregnancy & Older adults with decreased renal function

Fluoroquinolones

[ Choose ] Early infancy Throughout pregnancy Third trimester of pregnancy & Older adults with decreased renal function

Flag question: Question 4

Question 44 pts

Match the recommended treatment for UTI according to the assigned textbook for this course.

Use each option only once by selecting the option that is most true.

Group of answer choices

Ampicillin and gentamycin

[ Choose ] Breastfeeding women Children less than 6 years of age Infants Children between 6-12 years of age

Methenamine hippurate

[ Choose ] Breastfeeding women Children less than 6 years of age Infants Children between 6-12 years of age

Methenamine mandelate

[ Choose ] Breastfeeding women Children less than 6 years of age Infants Children between 6-12 years of age

Short-term Fluoroquinolones

[ Choose ] Breastfeeding women Children less than 6 years of age Infants Children between 6-12 years of age

Flag question: Question 5

Question 54 pts

Which antibiotic class is most likely to be given to someone with otitis media if there are no contraindications?

Group of answer choices

Penicillin

Cephalosporin

Tetracycline

Macrolide

Flag question: Question 6

Question 64 pts

If a patient is taking Bactrim and their creatinine clearance falls below 15 mL/min, what should the provider do?

Group of answer choices

Have patient continue the medication until it is complete.

It depends on how many doses the patient has taken.

Stop the drug immediately.

List the drug as an allergy and instruct the patient to stop taking it immediately.

Flag question: Question 7

Question 74 pts

Which patients should penicillins be used with extreme caution?

Group of answer choices

Patients with renal impairment, preexisting hearing impairment, and those receiving ototoxic and nephrotoxic drugs.

Patients with a history of severe allergic reactions to cephalosporins, or carbapenems.

Patients with QT prolongation.

Patients using valproate to control seizures.

Flag question: Question 8

Question 84 pts

Using your textbook, match the antibiotic class to the patient care concern for pregnant persons.

Use each option only once by selecting the option that is most true.

Group of answer choices

All appear to be safe for use in pregnancy

[ Choose ] Penicillins Sulfonamides Cephalosporins Tetracyclines Aminoglycosides

Although there are no well-controlled studies in pregnant women, evidence we do have suggests there is no second or third trimester fetal risk.

[ Choose ] Penicillins Sulfonamides Cephalosporins Tetracyclines Aminoglycosides

Animal studies reveal that these drugs can cause fetal harm in pregnancy. Thus this class of drugs should be avoided in during pregnancy.

[ Choose ] Penicillins Sulfonamides Cephalosporins Tetracyclines Aminoglycosides

There is evidence that use of this drug class in pregnancy can harm the fetus so they should not be used.

[ Choose ] Penicillins Sulfonamides Cephalosporins Tetracyclines Aminoglycosides

Systemic drugs in this class may cause birth defects, especially if taken during the first semester. If taken near term, the infant may develop kernicterus.

[ Choose ] Penicillins Sulfonamides Cephalosporins Tetracyclines Aminoglycosides

Flag question: Question 9

Question 94 pts

In patients with a creatinine clearance of 15-30 mL/min taking Bactrim, how should the dosing be adjusted?

Group of answer choices

Reduced by 50%

Reduced by 25%

Increased by 50%

Increased by 25%

Flag question: Question 10

Question 104 pts

Which antibiotic classes should have a culture and sensitivity prior to prescribing and which ones do not according to your textbook?

Group of answer choices

Culture

[ Choose ] Penicillins, Carbapenems, Vancomycin, Cephalosporins, Aminoglycosides Tetracyclines, Macrolides

Not indicated

[ Choose ] Penicillins, Carbapenems, Vancomycin, Cephalosporins, Aminoglycosides Tetracyclines, Macrolides

Flag question: Question 11

Question 114 pts

Match the drug class to the needed patient education.

Use each option only once by selecting the option that is most true.

Group of answer choices

Instruct patients to report increase in stool frequency.

[ Choose ] Cephalosporins Macrolides Tetracyclines Aminoglycosides

Advise patients to avoid prolonged exposure to sunlight

[ Choose ] Cephalosporins Macrolides Tetracyclines Aminoglycosides

Patients should be instructed that GI disturbances can be reduced by administering with meals.

[ Choose ] Cephalosporins Macrolides Tetracyclines Aminoglycosides

Patients must be instructed to report symptoms of ototoxicity.

[ Choose ] Cephalosporins Macrolides Tetracyclines Aminoglycosides

Flag question: Question 12

Question 124 pts

Acute otitis externa presents with what symptoms that differentiates it from otitis media to determine diagnosis and treatment?

Group of answer choices

Rapid-onset ear pain that include pruritis.

Tenderness associated with manipulation of the external ear.

Edema or erythema of the external auditory canal.

No tenderness associated with manipulation of the external ear.

Flag question: Question 13

Question 134 pts

What baseline data is needed to prescribe trimethoprim/sulfamethoxazole? (Select all that apply)

Group of answer choices

Establish an infection appropriate for this drug class exists

Complete blood count with white cell differential for prolonged therapy

Hepatic function if there is concern in may be compromised

Renal function if there is concern in may be compromised

Flag question: Question 14

Question 144 pts

Locate the Prescribers’ Digital Reference website (pdr.net) to answer this question. A patient is prescribed Amoxicillin for an infection. They have a creatinine clearance of 24mL/min. What dose of amoxicillin should they be prescribed?

Group of answer choices

no dosage adjustment needed

250-500mg PO every 12 hours

250-500 mg PO every 24 hours

875 mg Extended Release PO every 24 hours

Flag question: Question 15

Question 154 pts

Match the antibiotic class to the needed monitoring associated with that class.

Use each option only once by selecting the option that is most true.

Group of answer choices

Renal function in patients with renal disease

[ Choose ] Penicillins Aminoglycosides Trimethoprim/Sulfamethoxazole Vancomycin

Drug levels should be monitored during IV administration.

[ Choose ] Penicillins Aminoglycosides Trimethoprim/Sulfamethoxazole Vancomycin

Peaks and troughs as well as renal function

[ Choose ] Penicillins Aminoglycosides Trimethoprim/Sulfamethoxazole Vancomycin

CBC in patients with symptoms of blood disorders, CD4+ counts in patients with HIV and potassium 4 days after starting treatment in patients with possible hyperkalemia

[ Choose ] Penicillins Aminoglycosides Trimethoprim/Sulfamethoxazole Vancomycin

Flag question: Question 16

Question 164 pts

Which antibiotic drug class listed is known for all drugs within the class promoting the developments of a Clostridioidies difficile infection?

Group of answer choices

Tetracycline

Macrolide

Aminoglycoside

Cephalosporin

Flag question: Question 17

Question 174 pts

Match the penicillin drug to the penicillin class.

Use each option only once by selecting the option that is most true.

Group of answer choices

Penicillin G

[ Choose ] Narrow-spectrum penicillins: penicillinase sensitive Extended-spectrum penicillin (antipseudomonal penicillin) Broad-spectrum penicillins (aminopenicillins) Narrow-spectrum penicillins: penicillinase resistant (antistaphylococcal penicillins)

Penicillin V

Nafcillin

Oxacillin

Dicloxacillin

Ampicillin

Amoxicillin

Piperacillin

Flag question: Question 18

Question 184 pts

Which patients being treated with a penicillin are at high risk for toxicity? (Select all that apply)

Group of answer choices

renal impaired

acutely ill

very young

very old

active hepatitis

Flag question: Question 19

Question 194 pts

Using your textbook, match the antibiotic class to the patient care concern for breastfeeding patients.

Use each option only once by selecting the option that is most true.

Group of answer choices

Generally not expected to cause adverse effects in breastfed infants

[ Choose ] Penicillin Sulfonamides Amoxicillin Cephalosporins Gentamycin Tetracyclines

Safe for use in breastfeeding mothers.

[ Choose ] Penicillin Sulfonamides Amoxicillin Cephalosporins Gentamycin Tetracyclines

Data are lacking regarding transmission of some drugs in this class from mother to infant through breast milk.

[ Choose ] Penicillin Sulfonamides Amoxicillin Cephalosporins Gentamycin Tetracyclines

Should be avoided by breastfeeding women due to possible staining of teeth in breast fed infant.

[ Choose ] Penicillin Sulfonamides Amoxicillin Cephalosporins Gentamycin Tetracyclines

Secreted in breast milk. Breastfeeding women on these drugs should be warned that breastfeeding an infant younger than 2 months can cause kernicterus.

[ Choose ] Penicillin Sulfonamides Amoxicillin Cephalosporins Gentamycin Tetracyclines

Probably safe to use during lactation. There is limited information regarding its use in this way.

[ Choose ] Penicillin Sulfonamides Amoxicillin Cephalosporins Gentamycin Tetracyclines

Flag question: Question 20

Question 204 pts

Match the antibiotic class to the associated high-risk patient.

Use each option only once by selecting the option that is most true.

Group of answer choices

Patients using valproate to control seizures should not be placed on imipenem.

[ Choose ] Vancomycin Carbapenems Aminoglycosides Trimethoprim/Sulfamethoxazole Cephalosporins Macrolides Tetracyclines

Use with caution in patients with renal impairment.

[ Choose ] Vancomycin Carbapenems Aminoglycosides Trimethoprim/Sulfamethoxazole Cephalosporins Macrolides Tetracyclines

Contraindicated for patients with a history of allergic reactions to this drug class or severe reactions to penicillin.

[ Choose ] Vancomycin Carbapenems Aminoglycosides Trimethoprim/Sulfamethoxazole Cephalosporins Macrolides Tetracyclines

Contraindicated in pregnant women and in children younger than 8 years.

[ Choose ] Vancomycin Carbapenems Aminoglycosides Trimethoprim/Sulfamethoxazole Cephalosporins Macrolides Tetracyclines

Use with caution in patients with QT prolongation.

[ Choose ] Vancomycin Carbapenems Aminoglycosides Trimethoprim/Sulfamethoxazole Cephalosporins Macrolides Tetracyclines

Used with caution in patients with renal impairment, preexisting hearing impairment, and those receiving ototoxic and nephrotoxic drugs.

[ Choose ] Vancomycin Carbapenems Aminoglycosides Trimethoprim/Sulfamethoxazole Cephalosporins Macrolides Tetracyclines

Contraindicated for nursing mothers, pregnant women in the first trimester and also those near term, and infants younger than 2 months.

[ Choose ] Vancomycin Carbapenems Aminoglycosides Trimethoprim/Sulfamethoxazole Cephalosporins Macrolides Tetracyclines

Flag question: Question 21

Question 214 pts

Using your textbook, match the antibiotic class to the patient care concern for infants.

Use each option only once by selecting the option that is most true.

Group of answer choices

Third-generation drugs are used to treat bacterial infections in neonates as well as infants.

[ Choose ] Cephalosporins Sulfonamides Penicillins Aminoglycosides

Used safely in infants with bacterial infections, including syphilis, meningitis, and group A streptococcus.

[ Choose ] Cephalosporins Sulfonamides Penicillins Aminoglycosides

Approved to treat bacterial infections in infants younger than 8 days. Dosing is based on weight and length of gestation.

[ Choose ] Cephalosporins Sulfonamides Penicillins Aminoglycosides

Used in infants younger than 2 months can cause kernicterus, a potentially fatal condition.

[ Choose ] Cephalosporins Sulfonamides Penicillins Aminoglycosides

Flag question: Question 22

Question 224 pts

Trimethoprim should be avoided in patients with which deficiency?

Group of answer choices

Vitamin C

Vitamin A

Folate

Iodine

Flag question: Question 23

Question 234 pts

Using your textbook, match the antibiotic class to the therapeutic goal.

Use each option only once by selecting the option that is most true.

Group of answer choices

Treatment of serious infections, including C. diff. infection, infection with methicillin-resistant S. aureus, and serious infections caused by susceptible organisms in patients allergic to penicillin.

[ Choose ] Aminoglycosides Vancomycin Tetracyclines Macrolides

Treatment of infections sensitive to this class, acne, and periodontal disease.

[ Choose ] Aminoglycosides Vancomycin Tetracyclines Macrolides

Treatment of respiratory infections, infections caused by H. pylori, disseminated Mycobacterium, and as alternatives to penicillin in patients with penicillin allergy.

[ Choose ] Aminoglycosides Vancomycin Tetracyclines Macrolides

Treatment of serious infections caused by gram-negative aerobic bacilli.

[ Choose ] Aminoglycosides Vancomycin Tetracyclines Macrolides

Flag question: Question 24

Question 244 pts

Using your book and other resources you have available, match the antibiotic class to the prototype drug provided here.

Group of answer choices

Penicillin G

[ Choose ] Cephalosporins Aminoglycosides Macrolides Carbapenems Trimethoprim/Sulfamethoxazole Tetracyclines Penicillin

Cephalexin

[ Choose ] Cephalosporins Aminoglycosides Macrolides Carbapenems Trimethoprim/Sulfamethoxazole Tetracyclines Penicillin

Imipenem

[ Choose ] Cephalosporins Aminoglycosides Macrolides Carbapenems Trimethoprim/Sulfamethoxazole Tetracyclines Penicillin

Doxycycline

[ Choose ] Cephalosporins Aminoglycosides Macrolides Carbapenems Trimethoprim/Sulfamethoxazole Tetracyclines Penicillin

Erythromycin

[ Choose ] Cephalosporins Aminoglycosides Macrolides Carbapenems Trimethoprim/Sulfamethoxazole Tetracyclines Penicillin

Gentamicin

[ Choose ] Cephalosporins Aminoglycosides Macrolides Carbapenems Trimethoprim/Sulfamethoxazole Tetracyclines Penicillin

Bactrim

[ Choose ] Cephalosporins Aminoglycosides Macrolides Carbapenems Trimethoprim/Sulfamethoxazole Tetracyclines Penicillin

Flag question: Question 25

Question 254 pts

What is the likely causative agent for acute otitis media?

Group of answer choices

Staphylococcus Aureus

Pseudomonas

Streptococcus pneumoniae

Streptococcus pyogenes

Flag question: Question 26

Question 264 pts

Using your textbook, match the antibiotic class to the patient care concern for older adults.

Use each option only once by selecting the option that is most true.

Group of answer choices

Doses should be adjusted in older adults with renal dysfunction.

[ Choose ] Sulfonamides and Trimethoprim Tetracyclines Aminoglycosides Penicillins

Can interact with drugs, including digoxin. In the older adult who takes many medications, check for interactions.

[ Choose ] Sulfonamides and Trimethoprim Tetracyclines Aminoglycosides Penicillins

Caution must be used regarding decreased renal function in the older adult.

[ Choose ] Sulfonamides and Trimethoprim Tetracyclines Aminoglycosides Penicillins

Older patients are more likely to experience adverse effects, and when experienced, the effects are more likely to be severe. Life-threatening effects-including neutropenia, Stevens-Johnson syndrome, and toxic epidermal necrolysis-occur more frequently in older adults.

[ Choose ] Sulfonamides and Trimethoprim Tetracyclines Aminoglycosides Penicillins

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Advanced Pharmacology for Care of the Family

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