Formation of Renal Stones in Patients With Hyperparathyroidism
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Formation of Renal Stones in Patients With Hyperparathyroidism
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A 64-year-old Caucasian female presents to the clinic with vague symptoms of non- specific abdominal pain, myalgias, constipation, polyuria, and says she feels “fuzzy headed” much of the time. She had a fracture of her right metatarsal without trauma and currently is wearing a walking boot. She also had a bout of kidney stones a few weeks ago and she fortunately was able to pass the small stones without requiring lithotripsy or other interventions. She was told by the urologist to follow up with her primary care provider after the kidney stones has resolved.
The APRN examining the patient orders a Chem 12 which revealed a serum Ca++ of 13.1 mg/dl. The APRN believes the patient has primary hyperparathyroidism and refers the patient to an endocrinologist who does a complete work up and concurs with the APRN’s diagnosis.
Question:
What is the role of parathyroid hormone in the development of primary hyperparathyroidism?
Explain how a patient with hyperparathyroidism is at risk for bone fractures.
What serious consequences of hypoparathyroidism occur and why?
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