People who have chronic high blood pressure often have stiff and noncompliant arteries due to atherosclerosis.

Advanced Pathophysiology

Pick one of following three cases and present your case summary:

People who have chronic high blood pressure often have stiff and noncompliant arteries due to atherosclerosis. Explain how this will affect the following:

Blood flow through the arteries

Left ventricular afterload

Considering the normal function of endothelial cells, describe what you think would be the major clinical manifestations of endothelial dysfunction.

The student you are precepting asks about the difference between mitral regurgitation and mitral stenosis. She does not really understand the difference between the two disorders. How would you explain the following?

Primary pathophysiologic differences between mitral stenosis and mitral regurgitation.

Distinguishing clinical manifestations of each of the two disorders and their underlying mechanisms.

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