W5: Genetics and Bioethics
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W5: Genetics and Bioethics
This week we will explore the methods and impacts of gene editing on humans and plants
Gene editing and manipulation is a newer, but rapidly growing field. We have the ability to change, add or delete genes in human embryos, adults, and plants alike. We are going to explore both of these topics for this discussion. You are to CHOOSE ONE of the options below, read the information and articles, and answer the questions.
For your initial/original post:
Make sure to add a descriptive title so that others know what you are discussing.
Briefly summarize the main take-home points of the research articles noted for your option choice in the associated box below – make sure to include scientific terminology and discussion (remember, we are in a biology class!).
Follow the discussion grading criteria, guidelines and instructions for posting and replying to peers. Note: Keep your reply posts focused on biology. They should be substantive and demonstrate understanding to be eligible for maximum credit.
Option 1: Editing Human Embryos and Adults
With respect to gene editing in human embryos, most research is focused on fixing or removing harmful mutations that may cause diseases, but there are some fears of creating designer babies. In addition, we can edit the genes in adults, if we use a targeted approach. Read the articles below, and then respond to the prompt.
Questions to consider:
What is your take on the research?
Are there any benefits and/or costs?
Should we be focusing on this? Is there reason for concern?
Articles for Editing Human Embryos and Adults:
Andorno, R., Baylis, F., Darnovsky, M., Dickenson, D., Haker, H., Hasson, K., . . . Zuscinova, J. (2020, January 31). Geneva Statement on Heritable Human Genome Editing: The Need for Course Correction. Trends in Biotechnology, 38. (4), 351-354. Retrieved December 01, 2020, from https://www.cell.com/trends/biotechnology/fulltext/S0167-7799(19)30317-8?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0167779919303178%3Fshowall%3Dtrue
Flatow, I. (Host). (2018, November 30). The First CRISPR-Edited Babies Are (Probably) Here. Now What? [Audio podcast episode]. In Science Friday. WNYC Studios. Retrieved from https://www.sciencefriday.com/segments/the-first-crispr-edited-babies-are-probably-here-now-what/
Kaiser, J. (2017, November 15). A human has been injected with gene-editing tools to cure his disabling disease. Here’s what you need to know. Retrieved December 01, 2020, from https://www.sciencemag.org/news/2017/11/human-has-been-injected-gene-editing-tools-cure-his-disabling-disease-here-s-what-you
Ledford, H. (2017, October 03). CRISPR fixes disease gene in viable human embryos. Retrieved December 01, 2020, from https://www.nature.com/news/crispr-fixes-disease-gene-in-viable-human-embryos-1.22382
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