Course: Neurochemistry/Biochemistry in Psychopharmacology Program
Writing Assignment Instructions: Write scholarly APA-7th-style paper (7-9 pages in length, double-spaced, 12 pt font, references must include 3 peer-reviewed journal articles, which may be from list below)
Need a low similarity/originality score. Paper will be turn in through Turn-It-IN.
Theories of how psychotropic agents work include the monoamine and the receptor sensitivity hypotheses.
Develop a scholarly APA-style paper (7-10 pages in length) that identifies biochemical changes associated with these two hypotheses.
Your selections may include a discussion of changes in:
-Synthesis or metabolism of select neurotransmitters;
-And/OR how receptors change to modify responsivity to neurotransmitters;
-And/OR the biochemical processes associated with metabolic syndrome.
The peer-reviewed articles and publications provided below offer a diversity of topics and serve as examples to help you identify and focus on a specific condition.
Example articles for the Writing Assignment:
Farooqui, A. A., Farooqui, T., Panza, F., & Frisardi, V. (2012). Metabolic syndrome as a risk factor for neurological disorders. Cellular and Molecular Life Sciences : CMLS, 69(5), 741-762. https://doi.org/10.1007/s00018-011-0840-1
Goldberg, J. S., Bell, C. E., & Pollard, D. A. (2014). Revisiting the monoamine hypothesis of depression: A new perspective. Perspectives in Medicinal Chemistry, 2014(6), 1-8. https://doi.org/10.4137/PMC.S11375
Hinz, M., Stein, A., & Uncini, T. (2012). The discrediting of the monoamine hypothesis. International Journal of General Medicine, 5, 135-142. https://doi.org/10.2147/IJGM.S27824
Kimmel, M., Clive, M., Gispen, F., Guintivano, J., Brown, T., Cox, O., Beckmann, M. W., Kornhuber, J., Fasching, P. A., Osborne, L. M., Binder, E., Payne, J. L., & Kaminsky, Z. (2016). Oxytocin receptor DNA methylation in postpartum depression. Psychoneuroendocrinology, 69, 150-160. https://doi.org/10.1016/j.psyneuen.2016.04.008
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