Using the Cockcroft-Gault equation

1. Using the Cockcroft-Gault equation, calculate creatinine clearance for the

following patient: 70 year old female, 5’6” tall, 150 lb, SCr = 1.2 mg/dL.

Round your answer to the nearest 1 mL/min.

2. A 10-year-old female weighing 80 lbs presents with a urinary tract infection

and will be treated with sulfamethoxazole/trimethoprim (Bactrim®). Dosing

for this medication is typically based on the trimethoprim component.

Suspension is available as 200 mg of sulfamethoxazole and 40 mg of

trimethoprim in every 5 mL. Dosing for this indication is trimethoprim 8

mg/kg/day divided every 12 hours. How many milliliters of

sulfamethoxazole would be given with each dose? Round your answer to the nearest 0.5 ml.

nearest 0.5ml