The nurse is preparing to administer the antianginal drug nitroglycerin to a patient. The nurse knows which of the following are correct?

The nurse is preparing to administer the antianginal drug nitroglycerin to a patient. The nurse knows which of the following are correct? Select all that apply. Patches are applied once daily to a hairless area of skin. The site should be rotated to avoid local irritation. Long-acting preparations do not need to be tapered. Acts directly on vascular smooth muscle to promote vasodilation Nitroglycerin patches are used continuously Decreases the pain of exertional angina primarily by decreasing cardiac oxygen demand