What is the relationship that exists between the prevalence of a particular disease and the diagnostic specificity and sensitivity of a particular test undergoing validation?
What is the relationship that exists between the prevalence of a particular disease and the diagnostic specificity and sensitivity of a particular test undergoing validation? Explain your answer.
2. Explain how HAMAs interfere with immunoassays and determine what appropriate corrective action/s should be taken to correct the result.
3. What is solvent exclusion effect? Identify which test/s are affected by this phenomenon and explain how they interfere during testing and determine what corrective action/s can be taken to produce an accurate test result.
4. What is meant by the term “skill mix”? What is the application of this particular laboratory management principle in order to succeed in establishing a smooth and free flowing workflow inside the clinical laboratory? Explain your answer.
5. Give two (2) clinical scenarios where diurnal variation portrays a major role in the diagnosis, treatment and prognosis of patients suffering from a disease. You may support your answer with laboratory tests and other procedures.
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