CD40 Ligand Deficiency

At least three online resources (not including Wikipedia) must be listed below to receive credit for the assignment (see the rubric for the complete list requirements).  Answers to the questions should be in complete sentences, 1-10 sentences per answer.

Write about this disease:

CD40 Ligand Deficiency

Conduct research online in order to answer the following questions:

1. What are the cellular/molecular mechanisms that underlie this disease? (What are actual abnormalities or deficiencies causing the disease?)
2. How common is this disease? Are there any particular susceptibility groups? (Be sure to also consider any genetic or environmental susceptibilities.)
3. What are the disease symptoms?
4. What mechanisms are responsible for these disease symptoms? (Note: this is different from the answer to question 1.)
5. How is the diagnosis made? What particular clinical tests are used to make this diagnosis? This answer needs to be precise and specific. For example, blood test is not a sufficient answer. Your answer must indicate what cellular or molecular components are measured and how, and what particular parameters are used to make the disease diagnosis.
6. What is the prognosis for someone with this disease?
7. What are the treatment options? (Be sure to mention mechanisms of action of treatments and to consider novel treatments recently approved or in development.)

Present answers in worksheet format by including the above numbered questions written out with the answers provided below each question. Do NOT submit this assignment in essay format. Remember to list your resources in *APA format and include in text citations; and all writing must be in your own original words (zero points for plagiarism).

Bullet point answers for each questions please. NOT essay format. I want you to write about CD40 ligand deficiency.