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December 21, 2022

A 3-year old female is sent for testing because of recurring respiratory infections, including pneumonia

A 3-year old female is sent for testing because of recurring respiratory infections, including pneumonia. The results show decreased Ig levels, specially IgG. Although her WBC count is normal, her lymphocyte count was low. Flow cytometry was performed to determine if a particular subset of lymphocytes was low or missing. Using the results below, answer the following questions:

1. What do the flow cytometry patterns indicate about the population of lymphocytes affected?

2. What is the role of these cells in the immune system?

3. What do these results have to do with the child’s recurring infection?

4. Which further tests for infectious diseases should be performed?

Rodak, B.F. (2020) Rodak’s hematology: Clinical principles and applications. St. Louis, Missouri.

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