Consider the following scenarios and fill in the 2X2 table completely. Assume a sample size of 1000 for all problems.
Consider the following scenarios and fill in the 2X2 table completely. Assume a sample size of 1000 for all problems.
a. Disease prevalence is 20%, Sensitivity is 80%, Specificity is 90%.
Disease +
Disease –
Totals
Screening Pos
Screening Neg
Totals
PPV=__________ NPV=________
b. Disease prevalence is 5% Sensitivity is 80%, and Specificity is 90%.
Disease +
Disease –
Totals
Screening Pos
Screening Neg
Totals
PPV=______________ NPV=_________________________
Compared to A, what happens when our prevalence decreases?
c. Disease prevalence is 20%, Sensitivity is 80%, Specificity is 80%.
Disease +
Disease –
Totals
Screening Pos
Screening Neg
Totals
PPV=______________ NPV=_________________________
Compared to A, what happens when our specificity decreases?
d. Disease prevalence is 20%, Sensitivity is 70%, Specificity is 90%.
Disease +
Disease –
Totals
Screening Pos
Screening Neg
Totals
PPV=______________ NPV=___________________
Compared to A, what happens when our sensitivity decreases?
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