The study is described as “double blind”. What evidence was given to prove this occurred
Article- West, K. P., Jr, Katz, J., Khatry, S. K., LeClerq, S. C., Pradhan, E. K., Shrestha, S. R., Connor, P. B., Dali, S. M., Christian, P., Pokhrel, R. P., & Sommer, A. (1999). Double blind, cluster randomised trial of low dose supplementation with vitamin A or beta carotene on mortality related to pregnancy in Nepal. The NNIPS-2 Study Group. BMJ (Clinical research ed.), 318(7183), 570-575. https://doi.org/10.1136/bmj.318.7183.570
Answer the following questions
1- The study is described as “double blind”. What evidence was given to prove this occurred?
2-What were the exposure and outcome for this study and how were they described/defined?
3-What were the treatment and control groups and how were they randomized?
4-Based on the information provided in the article, did the investigators meet all their obligations to the study subjects? Why or why not? Address each one, providing specific examples.
5-Interpret the relative risk for beta carotene and mortality at 7-12 weeks post partum from Table 4.
6-What pieces of information were used to calculate the sample size needed for the study?
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