Health condition A has a heritability value of 0.72 whilst health condition B has a heritability value of 0.56.
Question 1
Health condition A has a heritability value of 0.72 whilst health condition B has a heritability value of 0.56. Which of the following statements relating to the heritability of these conditions are correct?
Select one or more:
1. Within a population 72% of the variance in condition A is determined by genes.
2. This individual risk of contracting condition A is 72%.
3. The individual risk of contracting condition B is 0.12.
4. Factors other than genes play a greater role in the development of condition A compared with condition B.
5. Within a population 44% of the variance in condition B is determined by factors other than genes.
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Question 2
Fill in the missing terms in the statement below:
In the developing human brain the subventricular zone differentiates into two different zones separated by the……………… . This process contributes to greater cortical complexity in humans as compared with rodents. As neurons migrate through the developing layers they extend small projections known as……………………to sense the surrounding environment. A chemical known as………………………………is used to help form stable synapses.
– BDNF
– filopodia
-inner fibre layer
– outer subventricular zone
– growth cones
– semaphorin 3a
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Question 3
Which of the following statements about epigenetic mechanisms are correct?
Select one or more:
1. Methylation can affect the transcription of DNA.
2. MicroRNA can bind to mRNA and cause destabilisation.
3. Methylation involves the addition of COCH3 groups to DNA.
4. Non-coding RNA cannot destablilise mRNA.
5. Epigenetic changes are thought to link maternal diabetes and neural tube disorders.
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