Mrs. A has been taking high doses of glucocorticoids for much of the past 2 years to control severe rheumatoid arthritis.
Mrs. A has been taking high doses of glucocorticoids for much of the past 2 years to control severe rheumatoid arthritis. She has now developed hypertension and type 2 diabetes and would like to stop taking the cortisone because of the unwanted changes in her appearance.
Discussion Questions
How does Cushing’s syndrome affect the individual?
Discuss how hypertension and diabetes have developed and the potential complications of these conditions.
Discuss other potential problems that Mrs. A may experience resulting from long-term use of glucocorticoids.
Mrs. L is a 63-year-old woman who reports constant back pain. Further inquiry into her medical history revealed that over the past 3 years, she has suffered fractures of her femur and wrist after minor falls. She experienced menopause at age 49. Mrs. L has a secretarial job, drives to work, and she “does not have time for exercise.” She reports that she consumes 8 to 10 cups of coffee a day and has been a smoker most of her adult life. She has not seen her physician recently nor had a recommended bone density test because of the time and cost involved.
Discussion Questions
Relate Mrs. L’s history to the diagnosis of osteoporosis. What risk factors are present, and how does each predispose to decreased bone density?
Explain the cause of pathological fractures in this patient.
How could osteoporosis have been prevented in Mrs. L?
Discuss the treatments available to the patient.
Weekly Outcomes
Weekly Objectives
Articulate alterations in structure and function of the endocrine and musculoskeletal systems. (CO 1)
Trace the impact that alterations in the endocrine and musculoskeletal systems have on the body. (CO 2)
Summarize the impact of alterations in the endocrine and musculoskeletal systems on homeostasis. (CO 3)
Understand normal endocrine and musculoskeletal system physiology.
Describe common types of endocrine and musculoskeletal system disorders: causes, clinical manifestations, diagnostic tests, and treatments.
Compare and contrast common endocrine and musculoskeletal conditions: causes, clinical manifestations, diagnostic tests, and treatments.
Apply understanding of alterations in the endocrine and musculoskeletal system across the lifespan to formulate care priorities.
Review the musculoskeletal systems function in bone formation, degradation, and homeostasis.
Examine responses to aging and its impact on pathophysiologic changes in the endocrine and musculoskeletal systems.
Describe how heredity and genetics influence pathophysiological alterations in the endocrine and musculoskeletal systems.
Main Topics and Concepts
Sub-Concepts with Exemplar
Alterations in the endocrine system
Alterations in physical structures
Alterations in function
Cancers of the endocrine system
Pathophysiologic endocrine response to aging
Genetic influences on endocrine system pathology
Alterations in musculoskeletal system
Alterations in physical structures
Alterations in function
Cancers of the musculoskeletal system
Pathophysiologic musculoskeletal response to aging
Genetic influences on musculoskeletal system pathology
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