Case Study 7 Disorders of Hemostasis

Case Study 7 Disorders of Hemostasis

Case Study 7 Disorders of Hemostasis

Leona is 52 years old and smokes. She is also overweight and has atherosclerosis. When she was given a two-week vacation from work, she packed up her bags and flew from Minnesota to Sydney, Australia, for the trip she always wanted to take. Unfortunately, just three days after she arrived, she was hospitalized when her left calf became inflamed, causing her considerable pain. The physician attending to her told her she developed a deep vein thrombosis.

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Explain, using your knowledge of hypercoagulability, why the trip to Australia contributed to Leona’s DVT?

Why was Leona already at risk for thrombus development?How does Leona’s atherosclerosis affect platelet function? Conversely, what is the effect of increased platelet activity on the development of atherosclerosis?

How do atherosclerosis and immobility promote changes in blood coagulation?

When Leona was in hospital, she received heparin therapy. Explain why this course of action was taken to treat her DVT. Why was she not given heparin tablets to take back to the hotel with her?

No Plegarism please, assignemnt will be checked with Turnitin. 

Will need 4 full pages double spaced for the case study, APA Style, Times New Roman, font 12, Title Page and a Reference page. 

References

Badimon, L., Padró, T., & Vilahur, G. (2012). Atherosclerosis, platelets and thrombosis in acute ischaemic heart disease. European Heart Journal , 60-74.

Diana, J. N. (2013). Tobacco Smoking and Atherosclerosis: Pathogenesis and Cellular Mechanisms.

Rissanen, P., et al,(2014). Weight change and blood coagulability and fibrinolysis in healthy obese women. Int J Obes Relat Metab Disord, 25(2):212-218,

Davis, J.W., et al,(2015) Effects of tobacco and non-tobacco cigarette smoking on endothelium and platelets. Clinical Pharmacological Therapy, 37(5):529-533

Ziegelstein, R.C., et al, (2016). Platelet function in patients with major depression. Intern Med J, 39(1):38-43