Propose two ways in which antibiotic resistance may develop in a bacterium
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Module 03 Content
This assignment contains four short answer questions. In some cases, there is a supplied list of keywords that should be used in developing your answer. You should use the knowledge gained in the readings and other assignments in this module. These are thought questions meant to help you process information that you have been exposed to in this module and if applicable, in previous modules. You may use outside sources, but you must use citations to show where you obtained the information. This is an untimed assignment. You only have one opportunity to complete this assignment.
Note: By starting this exam you agree to abide by the Academic Misconduct Policy set forth in the course syllabus. You acknowledge that your failure to do so could result in being expelled from the course.
Question 1
3 Points
Compare aerobic respiration, anaerobic respiration and fermentation. How are the processes similar? How are they different? How do these processes determine which environment the organism can live in?[Key terms to use in answer: electron transport chain, cytochrome, ATP, glucose, glycolysis, obligate aerobe, facultative anaerobe, microaerophile, obligate anaerobe, oxidase, catalase, peroxidase, CO2, organic acids and alcohols, alternative substrates (other than glucose)]
Question 2
3 Points
Using your knowledge of DNA recombination events to complete the following:
Propose two ways in which antibiotic resistance may develop in a bacterium
Describe how bacterial cells acquire the ability to produce toxins
(Use the following terminology in your answer: recombination, DNA, horizontal gene transfer, conjugation, transformation, transduction, pilus, F factor, transposable elements, transposons, pathogenicity islands)
Question 3
3 Points
Discuss how a pathogen causes an infection. Include definitions for primary pathogen, opportunistic pathogen, infection, disease (caused by a living organism), and various stages of pathogenesis. You can choose a specific organism to describe (like Orthomyxovirus and Influenza) or discuss a generalized infection.
Question 4
3 Points
Describe each type of infection in the following list and include the mode of transmission in each scenario. Use terms such as primary, secondary, healthcare-associated, STI, mixed, latent, toxemia, chronic, zoonotic, asymptomatic, local, and systemic to describe the types of infections (more than one term may apply, some may not apply to these conditions)
1) The development of Pneumocystisis pneumonia in an AIDS patient
2) Salmonellosis
3) Hantavirus pulmonary syndrome infection acquired while vacationing in a log cabin
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