Animal Physiology Homework
Please answer the following questions thoroughly based on the article, “Lifespan and Oxygen” attached.
1. How would youset up an experiment to answer this question?
a. Predictresults chart(s) of the experiment above.
2.Discussthe information presented on Fig 5. What does it tell us in the contextof aging and life span in reference to body size? What theory derivesfrom these data?
3. Whyis the cell membrane so susceptible to Oxidative damage? And why are cells withlarger proportion of PUFAs so sensitive to Oxidative
damage?
4. Howdoes the cell fix oxidative damages to its cell membrane? What is theevidence of it?
5. Discuss the effect of supplementation of antioxidants inthe diet of long-lived animals. IN which conditions it is beneficial andin which conditions it is not and why?
6. What are the main characteristics of the natural agingprocess and where does it take place?
7. Discuss the relationship between BMR and Maximum LifeSpan in mammals and birds and explain what basic theory of aging is supportedby this relationship.
8. What is thebasis of the oxidative stress theory of aging and what is its main postulate?
9. Figure 6 shows the decline of life-span with metabolicrate in birds and mammals. What does it mean to the rate of living theory ofaging? Can explain by the lines are not the same? (hint mammalsthermoregulate at 37C while birds thermoregulate at 41 C)
10. Intermittent fasting (look it up) is proposed as afeeding schedule that consists of fasting 16 to 18 hours every day. Individuals practicing this would eat all their daily food intake in a 6-8hours period. This “diet” may not be as effective in weightloss (because does not limit the amount of caloric intake, just the schedule itis consumed in) but it has been associated with the extension of healthylife. With what you have learned explain possible reasons why it maywork.
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